I'd like to offer a few females, some living, some not, to our line of Great Dudes.
Moms Mabley
Hedy Lamar
Jeanine Garafalo
Carol Burnett
Whoopi Goldberg
Goldie Hawn
Vicki Lawrence
Gilda Radner
Carrie Fisher
Jan Hooks
Bernadette Peters
Margaret Cho
Lily Tomlin
Madeline Kahn
Janis Joplin
Mary Travers
Mama Cass
More to come but I, er, lost my train of thought there. Feel free to suggest others.
Audrey Hepburn
Grace Hopper
Augusta Ada King, Countess of Lovelace
Helen Keller